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5-(N-甲基-N-异丁基)阿米洛利
5-(N-Methyl-N-isobutyl)-amiloride
产品别名
96861-65-3
5-(N-甲基-N-异丁基)阿米洛利
5-(N-Methyl-N-isobutyl)-amiloride
MIA
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H18ClN7O |
| Molecular weight | 299.76 |
| MDL number | MFCD00078567 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278228 |
| Application【应用】 | 5-(N-Methyl-N-isobutyl)amiloride is a potent blocker of the Na2/H+ antiport. 5-(N-Methyl-N-isobutyl)amiloride has been used to study early cellular response to acidosis. |
| Biochem/physiol Actions【生化/生理作用】 | Potent blocker of the Na+/H+ antiport. Possible antitumor agent. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥98% (TLC) |
| form【形式】 | powder |
| mp | 200-201 ℃ |
| solubility【溶解性】 | methanol: 9.80-10.20 mg/mL, clear, pale yellow to yellow |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(C)CN(C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N |
| InChI | 1S/C11H18ClN7O/c1-5(2)4-19(3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20) |
| InChI key | RVIUMPLAOXSSGN-UHFFFAOYSA-N |
| Gene Information | human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340) mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278) rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768) |
| packaging【包装】 | 25 mg in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
