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Anti-MEKKK 1 antibody produced in rabbit
产品别名
Anti-MEKKK 1 antibody produced in rabbit
MAPK/ERK kinase kinase kinase 1
Hematopoietic progenitor kinase
MEKKK 1
MEK kinase kinase 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-MEKKK 1 Antibody detects endogenous levels of total MEKKK 1 protein. The MEKKK 1 (mitogen-activated protein kinase kinase kinase 1) gene is mapped to human chromosome 5q11.2 and codes for serine/threonine kinase protein containing a plant homeodomain. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human MEKKK 1. Immunogen Range: 371-420 |
| Biochem/physiol Actions【生化/生理作用】 | MEKKK 1 (mitogen-activated protein kinase kinase kinase 1) controls different processes associated with inflammation and apoptosis. In response to upstream signals, the members of the MAPK (mitogen-activated protein kinase) family gets activated upon phosphorylation. MEKKK 1 possesses E3 ubiquitin ligase activity in relation to c-Jun protein stability and regulates the JNK (c-Jun NH2-terminal kinases) pathway. MEKKK 1 gene regulation is associated with acute respiratory distress syndrome. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 91 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:10000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | Q92918 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MAP3K1(4214) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
