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Anti-S1P2, C-Terminal antibody produced in rabbit
| 产品编号： | 3393365 |
| 规格： | ~1 mg/mL, fractionated antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-S1P2, C-Terminal antibody produced in rabbit
Anti-Endothelial Cell Differentiation Gene 5
Anti-EDG-5
基本信息
| MDL number | MFCD02686109 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | synthetic peptide (approximately 2.5 kDa, native) derived from the C-terminal region of the EDG-5/S1P2 receptor. |
| Application【应用】 | Anti-S1P2, C-Terminal antibody produced in rabbit is suitable for western blotting. |
| Biochem/physiol Actions【生化/生理作用】 | Sphingosine-1-phosphate receptor 2 (S1PR2 or S1P2) is a human gene encodeing a G protein-coupled receptor. It binds the lipid signaling molecule sphingosine 1-phosphate (S1P) and regulates vascular permeability along with S1P1. Activation of S1P2R in endothelial cells increases vascular permeability. It is a bioactive lysophospholipid capable of inducing a wide spectrum of biological responses. S1P acts as an intercellular mediator by interacting with the endothelial differentiation gene (EDG)/S1P family of G protein-coupled receptors. S1P2 receptor is involved in S1P-induced platelet aggregation and Rho kinase activation. Type 2 diabetes patient responds to S1P. |
| Physical form【外形】 | Supplied in phosphate buffered saline, pH 7.3, containing 0.08% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | fractionated antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~42 kDa by SDS-PAGE |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O95136 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... S1PR2(9294) |
