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Caspase-9 Inhibitor III-CAS 403848-57-7-Calbiochem
| 产品编号： | 4063544 |
| 规格： | The Caspase-9 Inhibitor III, also referenced under CAS 403848-57-7, controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications. |
| CAS NO： | 403848-57-7 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
403848-57-7
Caspase-9 Inhibitor III-CAS 403848-57-7-Calbiochem
Ac-LEHD-CMK
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H35ClN6O9 |
| Molecular weight | 587.02 |
| General description【一般描述】 | A potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM). A potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM). |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Target IC50: 70 nM against caspase-9 Primary Target caspase-9 Product does not compete with ATP. Reversible: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Ac-Leu-Glu-His-Asp-CMK |
| Other Notes【其他说明】 | Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated |
| color【颜色】 | white |
| solubility【溶解性】 | water: 1 mg/mL DMSO: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
