c-KIT (T670I), active, GST tagged human

NA.32

c-KIT (T670I) is a protein that belongs to the type I cytokine receptor family which combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. c-KIT (T670I) is a good candidate gene and the mutation of this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. The gene encoding this protein is localized on human chromosome 4q12.

The protein has a role in melanocyte development.

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

expressed in baculovirus infected Sf9 cells

PRECISIO^®

≥70% (SDS-PAGE)

buffered aqueous glycerol solution

11.2-16.8 nmol/min·mg

~73 kDa

NM_000222

dry ice

−70℃

human ... KIT(3815)

10 - Combustible liquids

WGK 1