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人半乳凝素-8 ELISA试剂盒
Human Galectin-8 ELISA Kit
| 产品编号： | 4119321 |
| 规格： | for cell culture supernatants, plasma, and serum samples |
| 包装规格： | 96 WELLS |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
人半乳凝素-8 ELISA试剂盒
Human Galectin-8 ELISA Kit
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | This ELISA antibody pair detects Human Galectin-8 (LGALS8) |
| Application【应用】 | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocolfor details. |
| Biochem/physiol Actions【生化/生理作用】 | Galectin-8 (Gal-8) is a member of “tandem-repeat” galectin family, possesses two carbohydrate binding domains linked by a short peptide. The short peptide accounts for Gal-8 cell adhesion and downstream signalling. Tumor cells, as well as normal tissues, express Gal-8. The expression level of Gal-8 is higher in multiple myeloma conditions and enhances adhesion to vascular endothelium. Galectin-8 binds to integrin selectively and inhibits cell adhesion and promotes apoptosis. Gal-8 interacts with integrin alpha and regulates neutrophil adhesion to endothelial cells and migration. Gal-8 ligand binds to cluster of differentiation 44 (CD44) and causes an inflammatory response in rheumatoid arthritis. Overexpression of Gal-8 plays a key role in metastasis of prostate cancer and cell survival by causing rearrangement of the cytoskeleton and E-cadherin expression. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable |
| input | sample type cell culture supernatant(s) sample type plasma sample type serum sample(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.16 ng/ml |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... LGALS8(3964) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
