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Panobinostat
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4139517 | 10 MG | 968 | 2-5天 | 4-6周 | |
| 4139517 | 50 MG | 3400 | 2-5天 | 4-6周 |
产品别名
404950-80-7
Panobinostat
LBH-589
LBH589
LBH 589
N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)-ethyl]-amino]methyl]phenyl]-2E-2-propenamide
(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
NVP-LBH589
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H23N3O2 |
| Molecular weight | 349.43 |
| MDL number | MFCD09833242 |
| Biochem/physiol Actions【生化/生理作用】 | Panobinostat (LBH589) is an orally active, potent, cinnamoyl hydroxamate-type pan-histone deacetylase inhibitor (class I HDAC1/2/3/8 IC50 = 2.5/13.2/2.1/277 nM; IIA HDAC4/5/7/9 IC50 = 203/7.8/531/5.7 nM; IIB HDAC6/10 IC50 = 10.5/2.3 nM, IV HDAC11 IC50 = 2.7 nM) with anti-cancer efficacy in vitro and in vivo. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC1=C(CCNCC2=CC=C(/C=C/C(NO)=O)C=C2)C3=CC=CC=C3N1 |
安全信息
| Pictograms【象形图】 | GHS05,GHS06,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 + H331 - H315 - H318 - H360 - H373 |
| Precautionary Statements | P202 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
