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PYCR1 human
| 产品编号： | 4140060 |
| 规格： | recombinant, expressed in E. coli, ≥90% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
PYCR1 human
PRO3
P5CR
PP222
Pyrroline-5-carboxylate reductase 1
PIG45
P5C
ARCL2B
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | PYCR1 is a universal housekeeping enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Physical form【外形】 | 0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.5) containing 10% glycerol. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | 35.5 kDa (339 aa, 1-319 aa + His Tag.) |
| packaging【包装】 | pkg of 50 μg |
| concentration【浓度】 | 0.5 mg/mL |
| UniProt accession no.【UniProt登记号】 | P32322 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PYCR1(5831) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
